In a breakthrough that could help ease drought of antibiotics, scientists from Massachusetts described the successful use of a test that uses the worm C. elegans to discover new antibiotics.
Frederick Ausubel and his colleagues described in the new study that the existing methods for identifying drugs for germs luca involves the addition of drugs to the cultures of microorganisms to see the results. These tests are sometimes not working properly, or may work for the organism but just be extremely toxic to humans or the host where the antibiotic use. These unintended consequences as well as increased resistance to antibiotics makes this lost efficiency cogeneration is the use of drugs anitmicrobianas.
A better test would be new possibilities for detection of antibiotics but in live animals infected with the bacteria to see the effects, not only in bacteria but also the whole body of the animal.
Scientists described the use of a new model consisting of a type of worm (C. elegans) infected with a type of bacteria (E. faecalis) and an automated robot high returns and tested the effects of 37,000 potential drugs. This bacterium causes life-threatening infections in humans and C. elegans nematodes are small worms that are widely used in scientific research.
In the tests identified 28 potential new drugs but unfortunately never informed of the effect against bacteria. Some of the possible new drugs worked in a completely different to existing antibiotics.
