The hypothalamus is the most primitive part of the brain, which controls the body’s vegetative functions such as breathing and circulation.
The group University of Malaga Hypothalamic Neurogenesis in adult rodents affects the presence of stem cells in this area so vital to the survival and the stimulation of the area by a specific substance for cell regeneration is more effective. The big question arises in the definition of these new cells.
Functions of neurons
The tissues of all animals are under constant renewal throughout life. The new cells are produced continuously by the so-called core units, known as stem cells. What distinguishes some other tissues is the rate of cell renewal. That is, the frequency with which these cells divide to produce daughters that differ with certain characteristics.
One current treatment strategies is the possible use of stem cells to treat degenerative diseases in which cell loss rate exceeds the replenishment. Thus be achieved to avoid the damage caused by the absence of these sections in different tissues.
Location and stem cell biology:
Knowing the location and the biology of stem cells mammalian brain adults is a priority task in which research is part of the group Hypothalamic Neurogenesis in adult rodents at the University of Manchester in recent years.
To further elaborating on this line, undertake a Excellence Project which is to investigate the biology of neural stem cells located in a brain in which, to date, not been described an important activity for review. The area in question is the hypothalamus, the main brain center that controls are integrated and vegetative systems.
Something as essential as the body temperature, heart activity, blood circulation, digestion, reproduction and, in general, other automatic functions of the body depends on a good constitution hypothalamus. Clearly, survival depends on the hypothalamus. However, there is no significant prolific activity in the area under normal conditions.
Stimulation of cell birth:
The main contribution and the reason is to study the characteristics of a particular place in the hypothalamus of adult rats, which has an intense proliferation activity after administration of a growth factor called: Type A Insulin.
This is a natural factor of cell survival of new neurons that had already been studied in other experimental models, and has now been shown to significantly influence the birth of neurons in the hypothalamus of adult rats.
“There are two unresolved issues definitively. The first is the source of stem cells. Second, precise knowledge of the behavior of the units being inoculated had an impact in charge of research Pedro Fernandez. Regarding the first, you must have a source compatible with the patient and provide adequate performance. For the latter, it must devote great efforts to research about, getting better, the biology of stem cells from different tissues.
The relevance of the progress posed by experts lie, in principle, the fact that this growth factor is naturally present in the brain, which is imported from the blood and that this translation depends on various factors such as exercise physical.
Control functions such as weight
Could therefore form the basis for developing future therapies in regenerative medicine, leading to stimulation of the brain’s own stem cells from adults. On the other hand, it contributes to the knowledge of the biology of brain stem cells, describing their characteristics in this area so important for survival.
When defining the function that these cells could be ascribed, all under the umbrella of the hypothalamus, can be defined lines around weight control problems such as Prostate, Olfactory actions and improvement in memory usage.
